Instruments for miRNA in situ Hybridization (ISH):
BioGenex is a pioneer in the design, development and manufacturing of advanced systems for automation of cell and tissue-based staining. The Xmatrx research systems (NANO, MINI and Infinity) are the direct result of our platform technology innovation. They offer a variety of automation, throughput and assay applications for translational and clinical research. Our key technology differentiators, including the eXACT temperature control and reaction micro-chamber, enable any slide-based assays such as immunohistochemistry (IHC), in situ hybridization (ISH), fluorescence in situ hybridization (FISH), immuno-fluorescence (IF), co-detection and multiplex applications (double and triple stains; IHC/ISH), in situ PCR, micro-RNA and special staining.
1. Xmatrx® Elite and Xmatrx® Infinity:
Features & Benefits:
- Intelligent and flexible system offering infinite possibilities – IHC, IF ISH, FISH, CISH, IF, Multiplexing and in situ PCR.
- Simultaneous optimization of up to 40 parameters in single run
- Reaction micro-chamber reduces micro-reagent consumption by up to 90%
- 40 independent thermocyclable (PCR) workstations
- Intuitive software designed for ease of use and flexibility
- Reports for inventory management and regulatory compliance
- Multiple slide processing options – Random, Continuous and STAT
2. NanoVIP:
Features & Benefits:
- All-in-One – FISH, in situ PCR and ISH
- Add micro-reagents manually to save cost
- Economical and affordable
- Flexible open system software - to create, edit and save protocols for future use
- Run 10 different protocols simultaneously
3. Xmatrx® MINI:
Features & Benefits:
- in situ PCR and FISH Work Station
- Hybridizer with eXACT™ temperatures
- 10 independent thermal cyclers
- Built-in touch screen display for easy operations
- On-board wash with effective waste drainage system
- Audio-visual alerts at every step for manual intervention
- User-friendly software with ability to add or delete cycles, store protocols for future use and perform up to 45 PCR cycles
4. Xmatrx® NANO:
Features & Benefits:
|
Specifications | Xmatrx® Infinity | NanoVIP | Xmatrx® MINI |
Automation | Full (baking through cover slip) |
Full Automation |
Work Station |
Run Time (full slide load) | Open System / User defined |
Open System / User defined |
Open System / User defined |
Temperature Range | Ambient to 105 oC |
Ambient to 105 oC |
Ambient to 105 oC |
Reagent Dispensing Volume | 10-850 µl |
10-850 uL |
NA |
Slide Capacity | 40 |
10 |
10 |
Reagent Capacity | 49 |
24 |
NA |
Bulk Reagent Carboy | 7 x 4 L |
6 x 1 L |
NA |
Waste Container | 8 L |
4 L |
2 L |
Languages enabled | English |
English, Italian |
English, Italian |
LIMS option | ✓ |
✓ |
✓ |
Protocols | Template / Self | Template / Self |
Template / Self |
Dimensions (D/W/H) | 29”/46”/59” | 20”/30”/20” |
19.5”/13”/8” |
Weight | 400 lb/ 182 kg | 106 lb/ 48 kg |
30 lb/ 13.6 kg |
Research Platforms /Application | IHC | ISH/CISH | Double Staining | Special Stains | FISH | IF | miRNA ISH |
Multiplexing (ISH + IHC) |
In Situ PCR |
Xmatrx® Infinity | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
NanoVIP | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Xmatrx® MINI | ✓ | ✓ | NA | NA | ✓ | ✓ | ✓ | ✓ | ✓ |